A, B, C, D, E, Frederick
December 25th, 2025 15:01I wasn't expecting it, but I went and checked the Madness collection after it was open to see if there was any 18th century fiction, and there was!
And then I saw it was a gift for me! Hooray!
The Frederician ABC (199 words) by Anonymous
Chapters: 1/1
Fandom: 18th Century CE RPF
Rating: Teen And Up Audiences
Warnings: No Archive Warnings Apply
Characters: Friedrich II von Preußen | Frederick the Great, Ernst Ahasverus von Lehndorff, Michael Gabriel Fredersdorf, Hans Hermann von Katte, Henri Alexandre de Catt, Joseph II von Österreich | Joseph II Holy Roman Emperor, Maria Theresia von Österreich | Maria Theresa of Austria (1717-1780), Voltaire (Writer), Stanisław August Poniatowski, Wilhelmine von Preußen | Wilhelmine of Prussia (1709-1758), Jacob Paul von Gundling, Johann Joachim Quantz, Ulrich Friedrich von Suhm, Francesco Algarotti, Peter Karl Christoph von Keith
Additional Tags: Silly, ABC Challenge, Yuletide Treat, Unconventionyule, Unconventional Format
Summary:
Need some help remembering who is who in 18th Century Prussia? Fear no more, the Frederician ABC is here.
Hallmark Christmas movie stuff
December 25th, 2025 18:48My alarm went off this morning (only at ten, but I needed it) to make sure I was up in time to walk Teddy before his humans were away for their Christmas lunch.
I thought I was the first person to make it downatairs this morning but while I was just getting to the bottom of the stairs I was already greeted by
angelofthenorth already in her usual comfy chair saying "Merry Christmas! Do you want some bucks fizz?" (Which is basically a pre-made mimosa. Luckily I'd been reminded of this recently by being offered it after the ceremony at the wedding we were at a few weeks ago; I'd been able to ask D then to remind me what it is.)
It's a lovely Christmas morning: chilly but not cold, usually pretty sunny, and dry.
It had been a week or so since Teddy and I had seen each other so we were both very excited to do so again.
On our walk, we saw a young probably-dad-type person heading to the recycling bin in front of his house with an armful of cardboard, the boxes already broken down. We grinned a greeting at each other.
A few houses down, a woman in pajamas and a big scarf was just trying to nip out to her car in front of the house, but since Teddy wants to say hello to everyone (human or dog) and assumes every human wants to pet him, so I couldn't drag him past her before she gave in and ruffled his ears and said "Merry Christmas" to me.
As we were leaving the park, I noticed we'd just been joined by two kids with the kind of lightsabers that make the noise when you hit them against each other, and a little scotty dog that I know is called Biscuit because they were getting told off/called over when they were ignoring the humans to say hello to Teddy.
I got home, opening the door to the lovely smells of
angelofthenorth already well into the process of cooking our amazing Christmas dinner.
FIC: Kamen Rider Gotchard, B-Robo Kabutack - Finders Keepers
December 25th, 2025 10:13Universe: Kamen Rider Gotchard, B-Robo Kabutack
Prompt: Mighty Morphin' Power Rangers: S02E08 - I, Eye Guy
Character(s): Kugimiya Licht, Harima Shiroi, Captain Tonborg, OCs
Rating: U
Warnings: N/A
Summary: This, thought Kugimiya Licht, was less than ideal, a waste of his time even. Through the course of their investigation, they had uncovered the cache of aged Octi-Eye cards buried in the ground, there was nothing contest. Finders keepers, as the children he had watched outside the window of his villa on the Palatine Hill had oft been moved to call out.
Length: 1858 words
Author's Notes: WWTHYWC! #22. Merry, merry Christmas, friends 🎄🎉🎁💝🍰 also: external link.
( Finders Keepers )
Life Day!!
December 25th, 2025 07:59
Happy Life Day everyone!! 🎄🎉🎁💝🍰
We crawled back in the car last night in the dead of night, and every inch of the way, I was convinced it was going to breakdown and we were going to be forced to push it back all the way to my mother's house. I was so angry with my work yester-day, so frustrated with everything, but to-day is going to be better; this is the one time of year, regardless of religion, that it feels like people try to be better, and I want to both join them in doing that and celebrate that with them too.
And to you also, friends, I hope you have a lovely, lovely day! 💝
Saint Norwegian Cod Day
December 24th, 2025 17:55But since this is mostly copy-pasting, I thought I'd do it...
Remember a couple years ago when I explained how my wife and I celebrate St. Salmon's Day on December 24 by eating salmon?
Furthermore, since my wife likes some of the Christmas trappings more than I do (tree, decorations, gift exchange, ritual meal), but is also an atheist who does not celebrate actual Christmas, we decided to call December 24 Salmon Day, because that is the day she makes our annual salmon (Brazilians celebrate Christmas on Dec 24). We were wishing each other a happy Salmon Day yesterday, and then today I wished her a happy "Day after Salmon Day," and she joked, "We are devotees of St. Salmon," and now Dec 25 is "Day after St. Salmon's Day" by sheer accretion of inside jokes. :D
This year, since she's living in Brazil again, she's visiting family for Xmas dinner, and we had this exchange on WhatsApp yesterday:
Her: i hope saint salmon doesn't get mad at me, I'm eating a different fish tomorrow
Me: We have made many offerings to St. Salmon, I'm sure you will be forgiven!
Then today:
Me: Happy Saint Other Fish's Day! 🤭
Her: happy saint fish's day to you too!
Me: You'll have to let me know what saint this is the day of.
Her: it is Norwegian cod day!
Her: in souffle format
Her: it is very holy
Her: 👀
Me: Happy Saint Norwegian Cod Day!
And later, after the dinner:
Her: damn, the cod souffle was amazing
I laughed a lot. Now back to work for me!
Yuletide: My Present!
December 24th, 2025 18:44Chapters: 1/1
Fandom: Moon is a Harsh Mistress - Robert A. Heinlein
Rating: Teen And Up Audiences
Warnings: No Archive Warnings Apply
Characters: Manuel Garcia O'Kelly Davis, Sidris (The Moon is a Harsh Mistress), Mimi, Greg, Bernardo de la Paz
Additional Tags: Pre-Canon
Summary:
Takes place just after Manny loses his arm
OMG OMG OMG, YES! This fic!
Merry Christmas: Scientists reverse Alzheimer's in mice [sci/bio/med]
December 24th, 2025 19:03By examining both human Alzheimer's brain tissue and multiple preclinical mouse models, the team identified a key biological failure at the center of the disease. They found that the brain's inability to maintain normal levels of a critical cellular energy molecule called NAD+ plays a major role in driving Alzheimer's. Importantly, maintaining proper NAD+ balance was shown to not only prevent the disease but also reverse it in experimental models.
Why This Approach Differs From Supplements
Dr. Pieper cautioned against confusing this strategy with over the counter NAD+-precursors. He noted that such supplements have been shown in animal studies to raise NAD+ to dangerously high levels that promote cancer. The method used in this research relies instead on P7C3-A20, a pharmacologic agent that helps cells maintain healthy NAD+ balance during extreme stress, without pushing levels beyond their normal range.
NAD+ levels naturally decline throughout the body, including the brain, as people age. When NAD+ drops too low, cells lose the ability to carry out essential processes needed for normal function and survival. The researchers discovered that this decline is far more severe in the brains of people with Alzheimer's. The same pattern was seen in mouse models of the disease.Note, potential conflict of interest: the head of the lab, Dr Pieper, above, has a serious commercial interest in this proving out:
[...]
Amyloid and tau abnormalities are among the earliest and most significant features of Alzheimer's. In both mouse models, these mutations led to widespread brain damage that closely mirrors the human disease. This included breakdown of the blood-brain barrier, damage to nerve fibers, chronic inflammation, reduced formation of new neurons in the hippocampus, weakened communication between brain cells, and extensive oxidative damage. The mice also developed severe memory and cognitive problems similar to those seen in people with Alzheimer's.
[...]
This approach built on the group's earlier work published in Proceeding of the National Academy of Sciences USA, which showed that restoring NAD+ balance led to both structural and functional recovery after severe, long-lasting traumatic brain injury. In the current study, the researchers used a well-characterized pharmacologic compound called P7C3-A20, developed in the Pieper laboratory, to restore NAD+ balance.
The results were striking. Preserving NAD+ balance protected mice from developing Alzheimer's, but even more surprising was what happened when treatment began after the disease was already advanced. In those cases, restoring NAD+ balance allowed the brain to repair the major pathological damage caused by the genetic mutations.
Both mouse models showed complete recovery of cognitive function. This recovery was also reflected in blood tests, which showed normalized levels of phosphorylated tau 217, a recently approved clinical biomarker used to diagnose Alzheimer's in people. These findings provided strong evidence of disease reversal and highlighted a potential biomarker for future human trials.
The technology is currently being commercialized by Glengary Brain Health, a Cleveland-based company co-founded by Dr. Pieper.The actual research article:
2025 Dec 22: Cell Reports Medicine [peer-reviewed scientific journal]: Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain by Kalyani Chaubey et al. (+35 other authors!):
Abstract:Full text here: https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00608-1
Alzheimer's disease (AD) is traditionally considered irreversible. Here, however, we provide proof of principle for therapeutic reversibility of advanced AD. In advanced disease amyloid-driven 5xFAD mice, treatment with P7C3-A20, which restores nicotinamide adenine dinucleotide (NAD+) homeostasis, reverses tau phosphorylation, blood-brain barrier deterioration, oxidative stress, DNA damage, and neuroinflammation and enhances hippocampal neurogenesis and synaptic plasticity, resulting in full cognitive recovery and reduction of plasma levels of the clinical AD biomarker p-tau217. P7C3-A20 also reverses advanced disease in tau-driven PS19 mice and protects human brain microvascular endothelial cells from oxidative stress. In humans and mice, pathology severity correlates with disruption of brain NAD+ homeostasis, and the brains of nondemented people with Alzheimer's neuropathology exhibit gene expression patterns suggestive of preserved NAD+ homeostasis. Forty-six proteins aberrantly expressed in advanced 5xFAD mouse brain and normalized by P7C3-A20 show similar alterations in human AD brain, revealing targets with potential for optimizing translation to patient care.
today EVRi actually managed to deliver a parcel, not only on time but early
December 24th, 2025 23:56... which meant I thought it was very funny when later said afternoon I became aware that there's ongoing scrutiny of their operations from the Business and Trade Committee (first link I could find, it's bedtime). Also very funny that the time from name change to shed legacy of being Awful to Nah You're Still Awful was approximately -5, on a more national scale than I'd previously clocked...
FIC: The Esther Greenwood School for Girls - A Proposal at the Esther Greenwood School for Girls
December 24th, 2025 22:44Universe: The Esther Greenwood School for Girls
Prompt: Christmas
Character(s): OCs
Rating: U
Warnings: N/A
Summary: The other girl’s face reddened tremendously and she yanked her bag out of the seat forcefully. “Like I’d ever marry you!” she declared, slamming the door hard.
Length: 1221 words
Author's Notes: WWTHYWC! #21. Illustration by Jericho Vilar. also: external link.
( A Proposal at the Esther Greenwood School for Girls )
david harbour; stranger things season 5 part 1 (+717)
December 24th, 2025 13:53Today in "hilarious ways to come out to my parents"...
December 24th, 2025 16:23I wrote and sent (luckily could retrieve in time!!) an email to them from my erik@ address, rather than the Gmail address I've had since 2004 and use for bank stuff and parent stuff and... that's about it now.
I have never even started to do such a thing before, I don't know what happened here! I'm feeling fine today, so for my brain to be so addled is very weird!
Luckily (??), emails sent from the erik@ account from my phone often bring up an error message that means I have to fiddle around a bit to get them sent, and when that happened this time my blood ran cold and I quickly deleted the email altogether. It never got from "outbox" to "sent" so that should be okay!
But sheesh what a near miss!
It was an email about my birthday present too so very obviously from me, I couldn't say it was just spam or something.
Fandom Fifty: #44
December 23rd, 2025 18:36SEVEN?! Okay, 3 of these were son's fault.
~ Love, Simon - I wound up unironically loving the way this played out. May have teared up a bit.
~ Solo: A Star Wars Story - Had been on the fence, fell for both Val and L3-37, GO ME FOR PICKING THE DOOMED ONES.
~ Venom - I had not kept up with comics, but I swear this version is almost like if every time The Maxx had been talking to himself, he'd been two people. I really did enjoy the film.
~ Bumblebee - LOL, I only just watched this in the past year. Twice. I really wish I had not waited but GO CHARLIE!
~ Aquaman - So I saw the reunion scene between Tom and Atlanna, and it hit my RexSoka buttons, so I watched it. Liked it a lot more than I had Wonder Woman!
~ Spider-Man: Into the Spider-Verse - OMG, so freaking awesome! I LOVE THIS FILM.
and my fave:
~ Black Panther - So this is where I fell back in love with some of the MCU again. There's not a Wakandan I don't love, even the antagonists. This made me give a damn about the BP property in ways I had not thought possible, and proves that you have to have the right creative effort leaders!
WHOOT: Highlander Gift fic
December 23rd, 2025 18:06Chapters: 1/1
Fandom: Highlander: The Series
Rating: General Audiences
Warnings: Creator Chose Not To Use Archive Warnings
Relationships: Amanda Darieux/Rebecca Horne
Characters: Amanda Darieux, Rebecca Horne, Rachel Ellenstein, Sunda Kastagir
Additional Tags: Fun, Adventure, Thievery, Humor
Summary:
Rebecca visits Kastagir at his fancy new hotel. Then Amanda shows up. Antics ensue.
[embodiment] huh
December 23rd, 2025 23:03Slightly to my surprise, earlier today I got a text from my GP saying approximately "yes your serum ferritin is now 'normal', but also, uh, by this we mean '15, with a reference range of 13-150, after six weeks of supplements', so... keep taking the supplements and we'll retest in six weeks!!!"
It is possible that the reason this actually got flagged at all was in fact that I've got a slightly elevated white cell count, and had I just had normal serum ferritin I'd have had to submit the "uhhh sooooo..." eConsult. Which I'd been gearing up to do, because the serum ferritin result showed up in the NHS app sooner than anything else!
Unfortunately, I had been working myself up to mentioning some Possible Additional Signs Of Concern in said eConsult (the various unimportant bleeding, like "there is usually old blood when I blow my nose BUT/AND I am very much using a steroid nasal spray every day") and I now have a solid excuse to keep putting it off for another six weeks, but hey. No longer officially anaemic! Pity about what's going to happen when I run out of supplementary iron, huh!
End of year meme
December 23rd, 2025 19:46I started introducing it this way in 2023:
The questions here sometimes feel random and sometimes aren't very relevant to me (how many one-night stands, bless; that feels like such a fossil of the height-of-LJ days when I first encountered this meme), but I do like it as a way to think a bit differently than I normally do about my life, and some things that had a big impact on me (like what a dog-hospital year it was for Gary) barely show up here. I do find myself at random points through the year noting things I do that I haven't done before, or wondering what my musical discovery might be, or whatever.
So here we go for 2025
1. What did you do in 2025 that you'd never done before?:
Wrote an extensive as the writer and basically project lead on a report at work -- never did this before, did it three times in a row this year.
Met a person from the internet and ended up having sex with them the same day. (Sorry if this is tmi, there will be no more details about it.)
2. Did you keep your new year's resolutions, and will you make more for next year?:
I didn't call it a resolution but when asked later about what I'd like to have this year that I lacked the previous one, I said
Another sexual and/or romantic partner? This feels impossible but so do the last four years' worth of things and they all happened!
Like three days after I wrote this I started talking to somoene on the social media site that's basically a kinky version of Facebook which, like regular Facebook, you can only access if you have an account and I was getting memes and events linked to by a friend until I got fed up and made an account. Six months later, I got a random message from someone who wrote a comment that I'd "liked" (as with Facebook, it tells you when people like your shit and then you can go look at their profile and all that) and in August I met him and it was fun to have a no-strings arrangement with a friend.
Will I make more for next year? I'm not sure, I think the coming year is more about keeping what I have stable: work, house, relationships, friendships, life....
( +47 )
50. What are your plans for 2026?
Laat year I wrote
Try to help everyone survive it with as much comfort and joy as we can manage, especially in the U.S. but everywhere really.
And I don't think I can improve on that answer either.
In a lot of ways it's been a rough year: the quick and steep decline of human rights in the U.S. has been hard to watch and harder to be affected by so personally. Work has been so difficult. I've had such a miserable experience trying to get referred for top surgery -- in the process bringing up so much medical fatphobia that I haven't even blogged about the whole saga, I can barely even think about it without panic or tears. Even my escapist hobby of MLB has been reminding me that billionaires feel
But in other ways it has also been a good year: it was really nice to be able to provide a safe landing place for
angelofthenorth and Mr Smith, it was nice to get through a November without anything (new) and terrible happening. Connections with the local queers have been deepened and I'm delighted that D and I are now on the small committee of people who've taken over from the two founders who have reasonably been able to step back and enjoy the thing they made as the ordinary attendees the rest of us have gotten to be the last two years.
Danceman December Dance Party #19: Kitagawa Rio
December 23rd, 2025 07:24
It's hard not to be aware at the time of writing this that Rio is graduating on 31st December. The situation surrounding this is not pleasant, and whilst Rio has resumed duties and wants to leave seemingly with her head held high, it feels like this overshadows everything—it reminds me of NECRONOMIDOL. I was going to be specific in relation to the members who later went on to form MANACLE, but I realise I could be talking about the exits of any member of any generation of NECRONOMIDOL. I don't think it's unnatural to complain about work, to complain about those you work with, but I think it also highlights the difficulty of trying to be in a group like Morning Musume whilst also trying to go to university, trying to live a normal life, to prepare for what comes after being an idol. Before that, however, in 2019 were the auditions, attempted not just by Rio but by fellow future fifteenth generation members Okamura Homare and Yamazaki Mei, as well as future Juice=Juice member Kawashima Mifu, and members who later joined ANGERME and OCHA NORMA, each of them passed with flying colours. Rio had spoken a lot when younger about wanting to join the entertainment industry, developing a fondness for Girls' Generation whilst still in the fifth grade. I wonder now if she would have any advice for her younger self; I wonder if achieving that ambition of becoming an idol made it mundane or if, in some way, it was so precious to her that she felt the need to downplay to others in order better to fit in? It's not the kind of question that can be asked, and, as such it's the kind of thing that will have to remain unanswered.
After only half a year or so in the group following her debut, Rio's experiences of being an idol were already informed by circumstances unlike any prior generation experienced. Her birthday shows in March 2020 were cancelled due to the onset of the plague, and yet amidst that, her first photobook was released, its only promotion being online. I don't know if this experience made her more dedicated than she would have been usually to this kind of thing, but since that first book during the height of covid, Rio has continually put out a new book each year—well, at least until this year. With the following year, however, and her fanclub established, Rio got to set tradition with annual birthday solo concerts, and despite joint injuries and covid, she carved out a place for herself within the structure of Morning Musume, a popularity that granted her the opportunity to go on tour with Okamura and Yamazaki alone just as the fifteenth generation. It is frustrating then that her suspension in April overshadows this success.
There are only a handful of days left with Kitagawa Rio, and without being in Japan for handshake events, I feel that many will miss out making peace with this moment. This, perhaps, is the real experience of the overseas fan. It's such a shame to end things this way. I really hope that Rio manages to find her place outside of Morning Musume.







